One man's experience with multiple myeloma

Tag: Chemo-Therapy

September 11, 2012

Let’s all pause for a moment and remember all those lost eleven years ago and pray for their families and friends.

After having trouble sleeping lat night, today was a pretty good; somewhat tired so I left work an hour early. I’ve had issues with nausea today and took ginger root capsules with lunch and dinner. This seems to be typical now on dosing days and for one or two days after. All-in-all, quite manageable.

September 10, 2012

Beginning of dosing cycle 7

6:25 AM – Took my cyclophosphamide.

7:30 AM – Took my dexamethasone and acyclovir along with my vitamins at breakfast.

9:50 AM – Arrived at Lynn Cancer Center.

10:10AM – CBC sample taken by Ana.

11:00 AM – Velcade injection given sub-cu by Karen.

– Arrived home feeling a little tired, as usual.

Spoke with Lisa about the curcumin. She said it would be perfectly OK to add this to my regimen. Went to Vitamin Shoppe who did not have the Drs. Best version, nor did the two closest stores. So I special ordered (2-4 weeks); I’ll order some on-line too.

August 20, 2012

Last night was uneventful by recent standards. No sign of Mr. Hyde. I slept quite well.

Day 14 of Dosing Cycle 6, dosing day 3 of 3.

6:35 AM – Took my cyclophosphamide.

7:45 AM – Took my dexamethasone and acyclovir along with my breakfast.

9:55 AM – Arrived at Lynn Cancer Center.

10:10 AM – CBC sample taken by Dorothea.

10:55 AM – Velcade shot given sub-cu by Paula. Paula gave me my CBC results. The results are good

August 19, 2012

Mr. Hyde returned in the early morning hours.

Feeling the muscle pain starting to return last night at about 11 pm, I took the acetaminophen and this time took 2 diphenhydramine. I doubt I shall try that again under these circumstances. Around 2:15 am, I was awakened by the muscle pain, but not quite completely because the diphenhydramine kept me groggy. I felt as though I was in a never-never land of hell because I couldn’t sleep and I couldn’t wake up. Only Kathleen’s calming back rub let me know that I really was going to be OK. I did fall asleep soon after.

Woke up feeling pretty good. Kathleen and I went to church at the Chapel of St. Andrew and the did some food shopping.

I look forward to the muscle pain side effect wearing off in time. All my other complaints that I have posted about have gone away: dysgeusia (not being able to taste salt or sour), constipation, nausea, etc. Even my peripheral neuropathy seems to be under control. You readers really do have immense power. All have gone away under the weight of your thoughts and prayers. The muscle pain will also go away in similar fashion. Thank you for all you do. Sometimes I must sound like a broken record, but I really do give thanks for all the good news: my myeloma numbers keep on improving and I have a good clinical plan worked out with Warren. God bless you all!!

I will not complain about my fatigue because I see it as healing time. God and my myeloma meds need time to work on me.

August 18, 2012

Like the evil twin, early Saturday morning was the Mr. Hyde to my Friday evening Dr. Jekyll.

Around 2 am, the muscle pain returned enough to prevent me from sleeping again until after 4:30 am. Besides trying the acetaminophen and diphenhydramine, I actually got on our recumbent bike to see if 20 minutes of light exercise might help; either it did or exhaustion took over.

Later in the morning, after a nice breakfast, Kathleen and I went to the beach. We got in some nice swimming in a very calm sea, and caught some good rays. Took a nap that afternoon. Then we met up with Mike and Robin at the Mellow Mushroom (a pizza place) for dinner. While the rain was heavy on our way there, it was a wonderful evening!

August 17, 2012

It’s now 9:45 pm. What a wonderful evening! I left work an hour early due to fatigue. After a rest, Kathleen and I made dinner, Caesar Salad with a nice Sterling Chardonnay. Later on, while watching Miss Marple solve the case of “The Murder in the Vicarage”, we enjoyed some Lindt chocolate and some Stock 84 brandy. Not stewed or anything, but I do feel better than I have in 2 weeks.

Thank you all for your prayers and thoughts because these have helped me get through what has been the most difficult period I’ve been through on this journey. God bless you all.

August 16, 2012

I saw Warren today for my regular appointment. He agreed that I should discontinue the Zometa as I wanted to. He also agreed that I could have 2 weeks off between cycle 6 (current) and the next. So, I’ll complete cycle 6 on Monday, and tentatively start cycle 7 on Sep 10th. He wants me to have a work up during the 2 weeks off, so I’ll have blood drawn on Aug 30th and see him on Sep 6th.

The idea is to give me a rest in the expectation that I can regain some strength before cycle 7. this is what I think I need. Warren thought that this was a very low risk approach to improve my quality of life.

August 15, 2012

My nausea issues decreased substantially overnight last night. Thank you especially to my Mom, Debbie, Jen, and Tracy for your extra prayers and thoughts. They worked!

My fortune cookie from lunch today had the following thought: “Try to channel excess energies into rejuvenation.” Yes, that is my life these days. All of my available energy goes to ridding myself of myeloma.

I may have found out the reason for some of my GI issues. While researching lactose intolerance on Wikipedia, I found a reference that said that Chemo-Therapy can be a cause of secondary lactose intolerance. I will discuss this with Warren tomorrow during my regular appointment.

August 13, 2012

Day 7 of Dosing Cycle 6, dosing day 2 of 3.

6:20 AM – Took my cyclophosphamide.

7:30 AM – Took my dexamethasone and acyclovir along with my breakfast.

9:55 AM – Arrived at Lynn Cancer Center.

10:10 AM – CBC sample taken by Carolyn.

10:45 AM – Velcade shot given sub-cu by Karen. Karen gave me my CBC results and the results of testing from the samples taken last Tuesday.

My CBC are normal. And the other results show that my M-Spike still comes down – it is now at 0.5. At this rate, I’ll need 4 more courses of treatment after this one to bring it to zero. The urine test results were all normal.

My thanks again to all of you offering your thoughts and prayers. These continue to help. May God bless you all!

August 11, 2012

I’ve updated my posting for July 28 to show two photographs.

Nausea, fatigue, and leg pain continue to be my major complaints. The nausea is sort of under control, but my appetite is still not good. Fatigue has been a large issue since I’ve not had the strength to remain at work for full days on Thursday and Friday this past week. The leg pain, or muscle pain may have an explainable cause:

In checking the package insert for the Zometa product, that I have now been dosed with three times, I see that muscle pain is a fairly common side effect. During my next appointment with Warren next Thursday, I will tell him of my desire to discontinue this therapy. Especially, when I consider that I don’t have the lytic lesions (small holes in my bones), for which Zometa is normally prescribed for myeloma patients. While there is some evidence that Zometa has anti-myeloma activity all by itself, I personally no longer think that this product is right for me.